Cargando…
The p53/microRNA connection in gastrointestinal cancer
The protein encoded by the TP53 gene is one of the most important suppressors of tumor formation, which is also frequently inactivated in gastrointestinal cancer. MicroRNAs (miRNAs) are small noncoding RNAs that inhibit translation and/or promote degradation of their target messenger RNAs. In recent...
Autores principales: | Rokavec, Matjaz, Li, Huihui, Jiang, Longchang, Hermeking, Heiko |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4198153/ https://www.ncbi.nlm.nih.gov/pubmed/25328413 http://dx.doi.org/10.2147/CEG.S43738 |
Ejemplares similares
-
Squalene epoxidase/SQLE is a candidate target for treatment of colorectal cancers with p53 mutation and elevated c-MYC expression
por: Du, Yuyun, et al.
Publicado: (2023) -
Paracrine Induction of Epithelial-Mesenchymal Transition Between Colorectal Cancer Cells and its Suppression by a p53/miR-192/215/NID1 Axis
por: Rokavec, Matjaz, et al.
Publicado: (2019) -
Soluble IL6R represents a miR-34a target: potential implications for the recently identified IL-6R/STAT3/miR-34a feed-back loop
por: Li, Huihui, et al.
Publicado: (2015) -
Characterization of a p53/miR-34a/CSF1R/STAT3 Feedback Loop in Colorectal Cancer
por: Shi, Xiaolong, et al.
Publicado: (2020) -
Nidogen-1/NID1 Function and Regulation during Progression and Metastasis of Colorectal Cancer
por: Rokavec, Matjaz, et al.
Publicado: (2023)