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Mimotope-Based Vaccines of Leishmania infantum Antigens and Their Protective Efficacy against Visceral Leishmaniasis
BACKGROUND: The development of cost-effective prophylactic strategies to prevent leishmaniasis has become a high-priority. The present study has used the phage display technology to identify new immunogens, which were evaluated as vaccines in the murine model of visceral leishmaniasis (VL). Epitope-...
Autores principales: | Costa, Lourena Emanuele, Goulart, Luiz Ricardo, Pereira, Nathália Cristina de Jesus, Lima, Mayara Ingrid Sousa, Duarte, Mariana Costa, Martins, Vivian Tamietti, Lage, Paula Sousa, Menezes-Souza, Daniel, Ribeiro, Tatiana Gomes, Melo, Maria Norma, Fernandes, Ana Paula, Soto, Manuel, Tavares, Carlos Alberto Pereira, Chávez-Fumagalli, Miguel Angel, Coelho, Eduardo Antonio Ferraz |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4198211/ https://www.ncbi.nlm.nih.gov/pubmed/25333662 http://dx.doi.org/10.1371/journal.pone.0110014 |
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