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Human Decidua-Derived Mesenchymal Stem Cells Differentiate into Functional Alveolar Type II-Like Cells that Synthesize and Secrete Pulmonary Surfactant Complexes
Lung alveolar type II (ATII) cells are specialized in the synthesis and secretion of pulmonary surfactant, a lipid-protein complex that reduces surface tension to minimize the work of breathing. Surfactant synthesis, assembly and secretion are closely regulated and its impairment is associated with...
Autores principales: | Cerrada, Alejandro, de la Torre, Paz, Grande, Jesús, Haller, Thomas, Flores, Ana I., Pérez-Gil, Jesús |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4198213/ https://www.ncbi.nlm.nih.gov/pubmed/25333871 http://dx.doi.org/10.1371/journal.pone.0110195 |
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