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Matrix Metalloproteinase 2 Contributes to Pancreatic Beta Cell Injury Induced by Oxidative Stress

OBJECTIVE: To investigate the role of matrix metalloproteinase 2 (MMP2) in pancreatic beta cell injury induced by oxidative stress. METHODS: Rat pancreatic beta cell line INS-1 cells were treated with advanced glycation end-products (AGE) to induce intracellular oxidative stress. Intracellular MMP2...

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Detalles Bibliográficos
Autores principales: Liu, Chongxiao, Wan, Xiaoyu, Ye, Tingting, Fang, Fang, Chen, Xueru, Chen, Yuanwen, Dong, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4198245/
https://www.ncbi.nlm.nih.gov/pubmed/25333278
http://dx.doi.org/10.1371/journal.pone.0110227