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Cohen’s h for detection of disease association with rare genetic variants
BACKGROUND: The power of the genome wide association studies starts to go down when the minor allele frequency (MAF) is below 0.05. Here, we proposed the use of Cohen’s h in detecting disease associated rare variants. The variance stabilizing effect based on the arcsine square root transformation of...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4198687/ https://www.ncbi.nlm.nih.gov/pubmed/25294186 http://dx.doi.org/10.1186/1471-2164-15-875 |