Cargando…

Severe rickets in a young girl caused by celiac disease: the tragedy of delayed diagnosis: a case report

BACKGROUND: Celiac disease is a systemic immune mediated disease which usually presents with gastrointestinal symptoms, but it may present with extra gastrointestinal manifestations such as metabolic bone disease and failure to thrive. This may lead to a delay in the diagnosis. CASE PRESENTATION: We...

Descripción completa

Detalles Bibliográficos
Autores principales: Al-Sharafi, Butheinah A, Al-Imad, Shafiq A, Shamshair, Amani M, Al-Faqeeh, Derhim H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4198728/
https://www.ncbi.nlm.nih.gov/pubmed/25292220
http://dx.doi.org/10.1186/1756-0500-7-701
_version_ 1782339773891870720
author Al-Sharafi, Butheinah A
Al-Imad, Shafiq A
Shamshair, Amani M
Al-Faqeeh, Derhim H
author_facet Al-Sharafi, Butheinah A
Al-Imad, Shafiq A
Shamshair, Amani M
Al-Faqeeh, Derhim H
author_sort Al-Sharafi, Butheinah A
collection PubMed
description BACKGROUND: Celiac disease is a systemic immune mediated disease which usually presents with gastrointestinal symptoms, but it may present with extra gastrointestinal manifestations such as metabolic bone disease and failure to thrive. This may lead to a delay in the diagnosis. CASE PRESENTATION: We present a 13 year old female from the middle east with an 8 year history of severe rickets causing multiple bone deformities leaving the child crippled with bowing of both of her arms and legs. The patient was also found to have growth failure, anemia and on further workup she was found to have celiac disease. CONCLUSION: We are presenting this case because it shows a severe case of rickets after malabsorption for many years. Celiac disease should be kept in mind as a cause of rickets in patients not responding to usual forms of treatment or when associated with other manifestations of malabsorption. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1186/1756-0500-7-701) contains supplementary material, which is available to authorized users.
format Online
Article
Text
id pubmed-4198728
institution National Center for Biotechnology Information
language English
publishDate 2014
publisher BioMed Central
record_format MEDLINE/PubMed
spelling pubmed-41987282014-10-17 Severe rickets in a young girl caused by celiac disease: the tragedy of delayed diagnosis: a case report Al-Sharafi, Butheinah A Al-Imad, Shafiq A Shamshair, Amani M Al-Faqeeh, Derhim H BMC Res Notes Case Report BACKGROUND: Celiac disease is a systemic immune mediated disease which usually presents with gastrointestinal symptoms, but it may present with extra gastrointestinal manifestations such as metabolic bone disease and failure to thrive. This may lead to a delay in the diagnosis. CASE PRESENTATION: We present a 13 year old female from the middle east with an 8 year history of severe rickets causing multiple bone deformities leaving the child crippled with bowing of both of her arms and legs. The patient was also found to have growth failure, anemia and on further workup she was found to have celiac disease. CONCLUSION: We are presenting this case because it shows a severe case of rickets after malabsorption for many years. Celiac disease should be kept in mind as a cause of rickets in patients not responding to usual forms of treatment or when associated with other manifestations of malabsorption. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1186/1756-0500-7-701) contains supplementary material, which is available to authorized users. BioMed Central 2014-10-08 /pmc/articles/PMC4198728/ /pubmed/25292220 http://dx.doi.org/10.1186/1756-0500-7-701 Text en © Al-Sharafi et al.; licensee BioMed Central Ltd. 2014 This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Case Report
Al-Sharafi, Butheinah A
Al-Imad, Shafiq A
Shamshair, Amani M
Al-Faqeeh, Derhim H
Severe rickets in a young girl caused by celiac disease: the tragedy of delayed diagnosis: a case report
title Severe rickets in a young girl caused by celiac disease: the tragedy of delayed diagnosis: a case report
title_full Severe rickets in a young girl caused by celiac disease: the tragedy of delayed diagnosis: a case report
title_fullStr Severe rickets in a young girl caused by celiac disease: the tragedy of delayed diagnosis: a case report
title_full_unstemmed Severe rickets in a young girl caused by celiac disease: the tragedy of delayed diagnosis: a case report
title_short Severe rickets in a young girl caused by celiac disease: the tragedy of delayed diagnosis: a case report
title_sort severe rickets in a young girl caused by celiac disease: the tragedy of delayed diagnosis: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4198728/
https://www.ncbi.nlm.nih.gov/pubmed/25292220
http://dx.doi.org/10.1186/1756-0500-7-701
work_keys_str_mv AT alsharafibutheinaha severericketsinayounggirlcausedbyceliacdiseasethetragedyofdelayeddiagnosisacasereport
AT alimadshafiqa severericketsinayounggirlcausedbyceliacdiseasethetragedyofdelayeddiagnosisacasereport
AT shamshairamanim severericketsinayounggirlcausedbyceliacdiseasethetragedyofdelayeddiagnosisacasereport
AT alfaqeehderhimh severericketsinayounggirlcausedbyceliacdiseasethetragedyofdelayeddiagnosisacasereport