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Severe rickets in a young girl caused by celiac disease: the tragedy of delayed diagnosis: a case report
BACKGROUND: Celiac disease is a systemic immune mediated disease which usually presents with gastrointestinal symptoms, but it may present with extra gastrointestinal manifestations such as metabolic bone disease and failure to thrive. This may lead to a delay in the diagnosis. CASE PRESENTATION: We...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4198728/ https://www.ncbi.nlm.nih.gov/pubmed/25292220 http://dx.doi.org/10.1186/1756-0500-7-701 |
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author | Al-Sharafi, Butheinah A Al-Imad, Shafiq A Shamshair, Amani M Al-Faqeeh, Derhim H |
author_facet | Al-Sharafi, Butheinah A Al-Imad, Shafiq A Shamshair, Amani M Al-Faqeeh, Derhim H |
author_sort | Al-Sharafi, Butheinah A |
collection | PubMed |
description | BACKGROUND: Celiac disease is a systemic immune mediated disease which usually presents with gastrointestinal symptoms, but it may present with extra gastrointestinal manifestations such as metabolic bone disease and failure to thrive. This may lead to a delay in the diagnosis. CASE PRESENTATION: We present a 13 year old female from the middle east with an 8 year history of severe rickets causing multiple bone deformities leaving the child crippled with bowing of both of her arms and legs. The patient was also found to have growth failure, anemia and on further workup she was found to have celiac disease. CONCLUSION: We are presenting this case because it shows a severe case of rickets after malabsorption for many years. Celiac disease should be kept in mind as a cause of rickets in patients not responding to usual forms of treatment or when associated with other manifestations of malabsorption. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1186/1756-0500-7-701) contains supplementary material, which is available to authorized users. |
format | Online Article Text |
id | pubmed-4198728 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2014 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-41987282014-10-17 Severe rickets in a young girl caused by celiac disease: the tragedy of delayed diagnosis: a case report Al-Sharafi, Butheinah A Al-Imad, Shafiq A Shamshair, Amani M Al-Faqeeh, Derhim H BMC Res Notes Case Report BACKGROUND: Celiac disease is a systemic immune mediated disease which usually presents with gastrointestinal symptoms, but it may present with extra gastrointestinal manifestations such as metabolic bone disease and failure to thrive. This may lead to a delay in the diagnosis. CASE PRESENTATION: We present a 13 year old female from the middle east with an 8 year history of severe rickets causing multiple bone deformities leaving the child crippled with bowing of both of her arms and legs. The patient was also found to have growth failure, anemia and on further workup she was found to have celiac disease. CONCLUSION: We are presenting this case because it shows a severe case of rickets after malabsorption for many years. Celiac disease should be kept in mind as a cause of rickets in patients not responding to usual forms of treatment or when associated with other manifestations of malabsorption. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1186/1756-0500-7-701) contains supplementary material, which is available to authorized users. BioMed Central 2014-10-08 /pmc/articles/PMC4198728/ /pubmed/25292220 http://dx.doi.org/10.1186/1756-0500-7-701 Text en © Al-Sharafi et al.; licensee BioMed Central Ltd. 2014 This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated. |
spellingShingle | Case Report Al-Sharafi, Butheinah A Al-Imad, Shafiq A Shamshair, Amani M Al-Faqeeh, Derhim H Severe rickets in a young girl caused by celiac disease: the tragedy of delayed diagnosis: a case report |
title | Severe rickets in a young girl caused by celiac disease: the tragedy of delayed diagnosis: a case report |
title_full | Severe rickets in a young girl caused by celiac disease: the tragedy of delayed diagnosis: a case report |
title_fullStr | Severe rickets in a young girl caused by celiac disease: the tragedy of delayed diagnosis: a case report |
title_full_unstemmed | Severe rickets in a young girl caused by celiac disease: the tragedy of delayed diagnosis: a case report |
title_short | Severe rickets in a young girl caused by celiac disease: the tragedy of delayed diagnosis: a case report |
title_sort | severe rickets in a young girl caused by celiac disease: the tragedy of delayed diagnosis: a case report |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4198728/ https://www.ncbi.nlm.nih.gov/pubmed/25292220 http://dx.doi.org/10.1186/1756-0500-7-701 |
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