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The Balance of Cell Surface and Soluble Type III TGF-β Receptor Regulates BMP Signaling in Normal and Cancerous Mammary Epithelial Cells()
Bone morphogenetic proteins (BMPs) are members of the TGF-β superfamily that are over-expressed in breast cancer, with context dependent effects on breast cancer pathogenesis. The type III TGF-β receptor (TβRIII) mediates BMP signaling. While TβRIII expression is lost during breast cancer progressio...
Autores principales: | Gatza, Catherine E., Elderbroom, Jennifer L., Oh, Sun Young, Starr, Mark D., Nixon, Andrew B., Blobe, Gerard C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Neoplasia Press
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4198744/ https://www.ncbi.nlm.nih.gov/pubmed/25077702 http://dx.doi.org/10.1016/j.neo.2014.05.008 |
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