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Cardioembolic Sources in Stroke Patients in South of Brazil

Background. Stroke is a leading cause of mortality and disability in Brazil and around the world. Cardioembolism is responsible for nearly 30% of the origins of ischemic stroke. Methods. We analyzed data of 256 patients with cardioembolic ischemic stroke (according to TOAST classification) who were...

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Detalles Bibliográficos
Autores principales: Porcello Marrone, Luiz Carlos, Farina Brunelli, João Pedro, Lutzky Saute, Ricardo, Henrique Tomasi, Gustavo, Cecchele Madeira, Bianca, Alves Martins, William, Dupont Rohr, Robson, Heck, Ana Paula, Botton, Luiz Ricardo, Martins de Castro, Marilia, Bodanese, Rodrigo, Bodanese, Luiz Carlos, Huf Marrone, Antônio Carlos, Costa da Costa, Jaderson
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4198824/
https://www.ncbi.nlm.nih.gov/pubmed/25349734
http://dx.doi.org/10.1155/2014/753780
Descripción
Sumario:Background. Stroke is a leading cause of mortality and disability in Brazil and around the world. Cardioembolism is responsible for nearly 30% of the origins of ischemic stroke. Methods. We analyzed data of 256 patients with cardioembolic ischemic stroke (according to TOAST classification) who were admitted into the Hospital São Lucas-PUCRS from October 2011 to January 2014. The cardioembolic subtype was divided into six subgroups: arrhythmias, valvular heart disease, coronary artery disease, cardiomyopathy, septal abnormalities, and intracardiac injuries. The prevalence of the most important cardiovascular risk factors and medications in use for prevention of systemic embolism by the time of hospital admission was analyzed in each patient. Results. Among 256 patients aged 60.2 +/− 6.9 years, 132 males, arrhythmias were the most common cause of cardioembolism corresponding to 50.7%, followed by valvular heart disease (17.5%) and coronary artery disease (16%). Hypertension (61.7%) and dyslipidemia (43.7%) were the most common risk factors. Less than 50% of patients with arrhythmias were using oral anticoagulants. Conclusions. Identifying the prevalence of cardioembolic stroke sources subgroups has become an increasingly important role since the introduction of new oral anticoagulants. In this study, arrhythmias (especially atrial fibrillation) were the main cause of cardioembolism.