Immortalization of T-Cells Is Accompanied by Gradual Changes in CpG Methylation Resulting in a Profile Resembling a Subset of T-Cell Leukemias()()()

We have previously described gene expression changes during spontaneous immortalization of T-cells, thereby identifying cellular processes important for cell growth crisis escape and unlimited proliferation. Here, we analyze the same model to investigate the role of genome-wide methylation in the im...

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Detalles Bibliográficos
Autores principales: Degerman, Sofie, Landfors, Mattias, Siwicki, Jan Konrad, Revie, John, Borssén, Magnus, Evelönn, Emma, Forestier, Erik, Chrzanowska, Krystyna H., Rydén, Patrik, Keith, W. Nicol, Roos, Göran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4198827/
https://www.ncbi.nlm.nih.gov/pubmed/25065939
http://dx.doi.org/10.1016/j.neo.2014.07.001

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