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Treatment of unresectable stage IV metastatic melanoma with aviscumine after anti-neoplastic treatment failure: a phase II, multi-centre study

BACKGROUND: Aviscumine, a recombinant plant protein, is an immune modulator that induces ribotoxic stress at the 28S ribosomal RNA subunit. In this way cytokine release and T-cell responses are enhanced. This phase II trial was conducted to test the efficacy and safety of aviscumine in patients with...

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Detalles Bibliográficos
Autores principales: Trefzer, Uwe, Gutzmer, Ralf, Wilhelm, Tabea, Schenck, Florian, Kähler, Katharina C, Jacobi, Volkmar, Witthohn, Klaus, Lentzen, Hans, Mohr, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4198912/
https://www.ncbi.nlm.nih.gov/pubmed/25324973
http://dx.doi.org/10.1186/s40425-014-0027-z