Association of MAPT haplotypes with Alzheimer’s disease risk and MAPT brain gene expression levels

INTRODUCTION: MAPT encodes for tau, the predominant component of neurofibrillary tangles that are neuropathological hallmarks of Alzheimer’s disease (AD). Genetic association of MAPT variants with late-onset AD (LOAD) risk has been inconsistent, although insufficient power and incomplete assessment...

Descripción completa

Detalles Bibliográficos
Autores principales: Allen, Mariet, Kachadoorian, Michaela, Quicksall, Zachary, Zou, Fanggeng, Chai, High Seng, Younkin, Curtis, Crook, Julia E, Pankratz, V Shane, Carrasquillo, Minerva M, Krishnan, Siddharth, Nguyen, Thuy, Ma, Li, Malphrus, Kimberly, Lincoln, Sarah, Bisceglio, Gina, Kolbert, Christopher P, Jen, Jin, Mukherjee, Shubhabrata, Kauwe, John K, Crane, Paul K, Haines, Jonathan L, Mayeux, Richard, Pericak-Vance, Margaret A, Farrer, Lindsay A, Schellenberg, Gerard D, Parisi, Joseph E, Petersen, Ronald C, Graff-Radford, Neill R, Dickson, Dennis W, Younkin, Steven G, Ertekin-Taner, Nilüfer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4198935/
https://www.ncbi.nlm.nih.gov/pubmed/25324900
http://dx.doi.org/10.1186/alzrt268

Ejemplares similares

Ejemplares similares