DNA phosphorothioate modifications influence the global transcriptional response and protect DNA from double-stranded breaks

The modification of DNA by phosphorothioate (PT) occurs when the non-bridging oxygen in the sugar-phosphate backbone of DNA is replaced with sulfur. This DNA backbone modification was recently discovered and is governed by the dndABCDE genes in a diverse group of bacteria and archaea. However, the b...

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Detalles Bibliográficos
Autores principales: Gan, Rui, Wu, Xiaolin, He, Wei, Liu, Zhenhua, Wu, Shuangju, Chen, Chao, Chen, Si, Xiang, Qianrong, Deng, Zixin, Liang, Dequan, Chen, Shi, Wang, Lianrong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4198939/
https://www.ncbi.nlm.nih.gov/pubmed/25319634
http://dx.doi.org/10.1038/srep06642

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