Constitutive phospholipid scramblase activity of a G Protein-coupled receptor*

Opsin, the rhodopsin apoprotein, was recently shown to be an ATP-independent flippase (or scramblase) that equilibrates phospholipids across photoreceptor disc membranes in mammalian retina, a process required for disc homeostasis. Here we show that scrambling is a constitutive activity of rhodopsin...

Descripción completa

Detalles Bibliográficos
Autores principales: Goren, Michael A., Morizumi, Takefumi, Menon, Indu, Joseph, Jeremiah S., Dittman, Jeremy S., Cherezov, Vadim, Stevens, Raymond C., Ernst, Oliver P., Menon, Anant K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4198942/
https://www.ncbi.nlm.nih.gov/pubmed/25296113
http://dx.doi.org/10.1038/ncomms6115

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4198942/
https://www.ncbi.nlm.nih.gov/pubmed/25296113
http://dx.doi.org/10.1038/ncomms6115

Ejemplares similares