Probing the effect of promoters on noise in gene expression using thousands of designed sequences

Genetically identical cells exhibit large variability (noise) in gene expression, with important consequences for cellular function. Although the amount of noise decreases with and is thus partly determined by the mean expression level, the extent to which different promoter sequences can deviate aw...

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Detalles Bibliográficos
Autores principales: Sharon, Eilon, van Dijk, David, Kalma, Yael, Keren, Leeat, Manor, Ohad, Yakhini, Zohar, Segal, Eran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2014
Materias:
Method
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4199362/
https://www.ncbi.nlm.nih.gov/pubmed/25030889
http://dx.doi.org/10.1101/gr.168773.113

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4199362/
https://www.ncbi.nlm.nih.gov/pubmed/25030889
http://dx.doi.org/10.1101/gr.168773.113

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