Large-scale identification of chemically induced mutations in Drosophila melanogaster

Forward genetic screens using chemical mutagens have been successful in defining the function of thousands of genes in eukaryotic model organisms. The main drawback of this strategy is the time-consuming identification of the molecular lesions causative of the phenotypes of interest. With whole-geno...

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Detalles Bibliográficos
Autores principales: Haelterman, Nele A., Jiang, Lichun, Li, Yumei, Bayat, Vafa, Sandoval, Hector, Ugur, Berrak, Tan, Kai Li, Zhang, Ke, Bei, Danqing, Xiong, Bo, Charng, Wu-Lin, Busby, Theodore, Jawaid, Adeel, David, Gabriela, Jaiswal, Manish, Venken, Koen J.T., Yamamoto, Shinya, Chen, Rui, Bellen, Hugo J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2014
Materias:
Method
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4199363/
https://www.ncbi.nlm.nih.gov/pubmed/25258387
http://dx.doi.org/10.1101/gr.174615.114

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