Decoding ChIP-seq with a double-binding signal refines binding peaks to single-nucleotides and predicts cooperative interaction

The comprehension of protein and DNA binding in vivo is essential to understand gene regulation. Chromatin immunoprecipitation followed by sequencing (ChIP-seq) provides a global map of the regulatory binding network. Most ChIP-seq analysis tools focus on identifying binding regions from coverage en...

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Detalles Bibliográficos
Autores principales: Gomes, Antonio L.C., Abeel, Thomas, Peterson, Matthew, Azizi, Elham, Lyubetskaya, Anna, Carvalho, Luís, Galagan, James
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2014
Materias:
Method
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4199365/
https://www.ncbi.nlm.nih.gov/pubmed/25024162
http://dx.doi.org/10.1101/gr.161711.113

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