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Genome-wide DNA methylation patterns in LSH mutant reveals de-repression of repeat elements and redundant epigenetic silencing pathways

Cytosine methylation is critical in mammalian development and plays a role in diverse biologic processes such as genomic imprinting, X chromosome inactivation, and silencing of repeat elements. Several factors regulate DNA methylation in early embryogenesis, but their precise role in the establishme...

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Detalles Bibliográficos
Autores principales: Yu, Weishi, McIntosh, Carl, Lister, Ryan, Zhu, Iris, Han, Yixing, Ren, Jianke, Landsman, David, Lee, Eunice, Briones, Victorino, Terashima, Minoru, Leighty, Robert, Ecker, Joseph R., Muegge, Kathrin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4199375/
https://www.ncbi.nlm.nih.gov/pubmed/25170028
http://dx.doi.org/10.1101/gr.172015.114