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Sodium ferulate lowers portal pressure in rats with secondary biliary cirrhosis through the RhoA/Rho-kinase signaling pathway: A preliminary study

Cirrhotic rats show higher expression levels of hepatic RhoA and Rho-kinase than normal healthy rats, and the activation of this signaling pathway leads to portal hypertension. Sodium ferulate (SF) has been shown to decrease the production of geranylgeranyl pyrophosphate (GGPP), a substance essentia...

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Detalles Bibliográficos
Autores principales: WEI, LAI, YANG, JUAN, WANG, MIN, XU, SHENG-NAN, LIANG, HUA-MIN, ZHOU, QI
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4199412/
https://www.ncbi.nlm.nih.gov/pubmed/25174394
http://dx.doi.org/10.3892/ijmm.2014.1905