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Sodium ferulate lowers portal pressure in rats with secondary biliary cirrhosis through the RhoA/Rho-kinase signaling pathway: A preliminary study
Cirrhotic rats show higher expression levels of hepatic RhoA and Rho-kinase than normal healthy rats, and the activation of this signaling pathway leads to portal hypertension. Sodium ferulate (SF) has been shown to decrease the production of geranylgeranyl pyrophosphate (GGPP), a substance essentia...
Autores principales: | WEI, LAI, YANG, JUAN, WANG, MIN, XU, SHENG-NAN, LIANG, HUA-MIN, ZHOU, QI |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4199412/ https://www.ncbi.nlm.nih.gov/pubmed/25174394 http://dx.doi.org/10.3892/ijmm.2014.1905 |
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