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Break-Induced Replication Requires DNA Damage-Induced Phosphorylation of Pif1 and Leads to Telomere Lengthening

Broken replication forks result in DNA breaks that are normally repaired via homologous recombination or break induced replication (BIR). Mild insufficiency in the replicative ligase Cdc9 in budding yeast Saccharomyces cerevisiae resulted in a population of cells with persistent DNA damage, most lik...

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Detalles Bibliográficos
Autores principales: Vasianovich, Yulia, Harrington, Lea A., Makovets, Svetlana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4199488/
https://www.ncbi.nlm.nih.gov/pubmed/25329304
http://dx.doi.org/10.1371/journal.pgen.1004679