The DAF-16 FOXO Transcription Factor Regulates natc-1 to Modulate Stress Resistance in Caenorhabditis elegans, Linking Insulin/IGF-1 Signaling to Protein N-Terminal Acetylation

The insulin/IGF-1 signaling pathway plays a critical role in stress resistance and longevity, but the mechanisms are not fully characterized. To identify genes that mediate stress resistance, we screened for C. elegans mutants that can tolerate high levels of dietary zinc. We identified natc-1, whic...

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Detalles Bibliográficos
Autores principales: Warnhoff, Kurt, Murphy, John T., Kumar, Sandeep, Schneider, Daniel L., Peterson, Michelle, Hsu, Simon, Guthrie, James, Robertson, J. David, Kornfeld, Kerry
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4199503/
https://www.ncbi.nlm.nih.gov/pubmed/25330323
http://dx.doi.org/10.1371/journal.pgen.1004703

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4199503/
https://www.ncbi.nlm.nih.gov/pubmed/25330323
http://dx.doi.org/10.1371/journal.pgen.1004703

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