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Tpz1-Ccq1 and Tpz1-Poz1 Interactions within Fission Yeast Shelterin Modulate Ccq1 Thr93 Phosphorylation and Telomerase Recruitment

In both fission yeast and humans, the shelterin complex plays central roles in regulation of telomerase recruitment, protection of telomeres against DNA damage response factors, and formation of heterochromatin at telomeres. While shelterin is essential for limiting activation of the DNA damage chec...

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Detalles Bibliográficos
Autores principales: Harland, Jennifer L., Chang, Ya-Ting, Moser, Bettina A., Nakamura, Toru M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4199508/
https://www.ncbi.nlm.nih.gov/pubmed/25330395
http://dx.doi.org/10.1371/journal.pgen.1004708