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Attenuation of Acetylcholine Activated Potassium Current (I(KACh)) by Simvastatin, Not Pravastatin in Mouse Atrial Cardiomyocyte: Possible Atrial Fibrillation Preventing Effects of Statin

Statins, 3-hydroxy-3-methyl-glutaryl-CoA reductase inhibitors, are associated with the prevention of atrial fibrillation (AF) by pleiotropic effects. Recent clinical trial studies have demonstrated conflicting results on anti-arrhythmia between lipophilic and hydrophilic statins. However, the underl...

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Detalles Bibliográficos
Autores principales: Cho, Kyoung-Im, Cha, Tae-Joon, Lee, Su-Jin, Shim, In-Kyeung, Zhang, Yin Hua, Heo, Jung-Ho, Kim, Hyun-Su, Kim, Sung Joon, Kim, Kyoung-Lyoung, Lee, Jae-Woo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4199526/
https://www.ncbi.nlm.nih.gov/pubmed/25329899
http://dx.doi.org/10.1371/journal.pone.0106570