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Inhibition or Knockdown of ABC Transporters Enhances Susceptibility of Adult and Juvenile Schistosomes to Praziquantel
Parasitic flatworms of the genus Schistosoma cause schistosomiasis, a neglected tropical disease that affects hundreds of millions. Treatment of schistosomiasis depends almost entirely on the drug praziquantel (PZQ). Though essential to treating and controlling schistosomiasis, a major limitation of...
Autores principales: | Kasinathan, Ravi S., Sharma, Lalit Kumar, Cunningham, Charles, Webb, Thomas R., Greenberg, Robert M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4199547/ https://www.ncbi.nlm.nih.gov/pubmed/25330312 http://dx.doi.org/10.1371/journal.pntd.0003265 |
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