Clinically Approved Iron Chelators Influence Zebrafish Mortality, Hatching Morphology and Cardiac Function

Iron chelation therapy using iron (III) specific chelators such as desferrioxamine (DFO, Desferal), deferasirox (Exjade or ICL-670), and deferiprone (Ferriprox or L1) are the current standard of care for the treatment of iron overload. Although each chelator is capable of promoting some degree of ir...

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Detalles Bibliográficos
Autores principales: Hamilton, Jasmine L., Hatef, Azadeh, Imran ul-haq, Muhammad, Nair, Neelima, Unniappan, Suraj, Kizhakkedathu, Jayachandran N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4199627/
https://www.ncbi.nlm.nih.gov/pubmed/25329065
http://dx.doi.org/10.1371/journal.pone.0109880

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