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Exploring the Anti-Cancer Activity of Novel Thiosemicarbazones Generated through the Combination of Retro-Fragments: Dissection of Critical Structure-Activity Relationships

Thiosemicarbazones (TSCs) are an interesting class of ligands that show a diverse range of biological activity, including anti-fungal, anti-viral and anti-cancer effects. Our previous studies have demonstrated the potent in vivo anti-tumor activity of novel TSCs and their ability to overcome resista...

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Detalles Bibliográficos
Autores principales:	Serda, Maciej, Kalinowski, Danuta S., Rasko, Nathalie, Potůčková, Eliška, Mrozek-Wilczkiewicz, Anna, Musiol, Robert, Małecki, Jan G., Sajewicz, Mieczysław, Ratuszna, Alicja, Muchowicz, Angelika, Gołąb, Jakub, Šimůnek, Tomáš, Richardson, Des R., Polanski, Jaroslaw
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4199632/ https://www.ncbi.nlm.nih.gov/pubmed/25329549 http://dx.doi.org/10.1371/journal.pone.0110291

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