Cargando…
Loss of Optineurin In Vivo Results in Elevated Cell Death and Alters Axonal Trafficking Dynamics
Mutations in Optineurin have been associated with ALS, glaucoma, and Paget’s disease of bone in humans, but little is known about how these mutations contribute to disease. Most of the cellular consequences of Optineurin loss have come from in vitro studies, and it remains unclear whether these same...
| Autores principales: | , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2014
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4199637/ https://www.ncbi.nlm.nih.gov/pubmed/25329564 http://dx.doi.org/10.1371/journal.pone.0109922 |