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How Structure Defines Affinity in Protein-Protein Interactions

Protein-protein interactions (PPI) in nature are conveyed by a multitude of binding modes involving various surfaces, secondary structure elements and intermolecular interactions. This diversity results in PPI binding affinities that span more than nine orders of magnitude. Several early studies att...

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Detalles Bibliográficos
Autores principales:	Erijman, Ariel, Rosenthal, Eran, Shifman, Julia M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4199723/ https://www.ncbi.nlm.nih.gov/pubmed/25329579 http://dx.doi.org/10.1371/journal.pone.0110085

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