Cargando…

Evaluation of the efficacy, safety, and acceptability of an eyelid warming device for the treatment of meibomian gland dysfunction

Meibomian gland dysfunction (MGD) is widespread and has significant impact on patients’ quality of life. Eyelid hygiene is the mainstay of treatment but is unstandardized and requires commitment from the patient and encouragement from the ophthalmologist. Blephasteam(®) is an eyelid warming device d...

Descripción completa

Detalles Bibliográficos
Autores principales: Benitez del Castillo, José Manuel, Kaercher, Thomas, Mansour, Khaled, Wylegala, Edward, Dua, Harminder
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4199825/
https://www.ncbi.nlm.nih.gov/pubmed/25336900
http://dx.doi.org/10.2147/OPTH.S68201
_version_ 1782339982410645504
author Benitez del Castillo, José Manuel
Kaercher, Thomas
Mansour, Khaled
Wylegala, Edward
Dua, Harminder
author_facet Benitez del Castillo, José Manuel
Kaercher, Thomas
Mansour, Khaled
Wylegala, Edward
Dua, Harminder
author_sort Benitez del Castillo, José Manuel
collection PubMed
description Meibomian gland dysfunction (MGD) is widespread and has significant impact on patients’ quality of life. Eyelid hygiene is the mainstay of treatment but is unstandardized and requires commitment from the patient and encouragement from the ophthalmologist. Blephasteam(®) is an eyelid warming device designed to be an easy-to-use and standardized treatment for MGD. In the present study, 73 patients were treated for 21 days with twice daily Blephasteam(®) sessions. The primary efficacy variable, a symptomatology visual analog scale score, declined from 63.07±21.23 (mean ± standard deviation) on day 0 to 41.90±25.49 on day 21. There were also improvements in a number of secondary efficacy variables including subjective ocular symptoms and clinical signs and symptoms of MGD and dry eye, though tear film breakup time and tear osmolarity were not improved. Global efficacy was assessed as satisfactory or very satisfactory in 83.8% of cases. Patient-reported subjective ocular symptoms declined during the study, and a majority of patients rated the efficacy of Blephasteam(®) as satisfactory or very satisfactory. Most patients found the device comfortable and were able to continue with normal activities (reading, watching TV, using a computer) during the Blephasteam(®) session. No safety or tolerability issues were identified.
format Online
Article
Text
id pubmed-4199825
institution National Center for Biotechnology Information
language English
publishDate 2014
publisher Dove Medical Press
record_format MEDLINE/PubMed
spelling pubmed-41998252014-10-21 Evaluation of the efficacy, safety, and acceptability of an eyelid warming device for the treatment of meibomian gland dysfunction Benitez del Castillo, José Manuel Kaercher, Thomas Mansour, Khaled Wylegala, Edward Dua, Harminder Clin Ophthalmol Original Research Meibomian gland dysfunction (MGD) is widespread and has significant impact on patients’ quality of life. Eyelid hygiene is the mainstay of treatment but is unstandardized and requires commitment from the patient and encouragement from the ophthalmologist. Blephasteam(®) is an eyelid warming device designed to be an easy-to-use and standardized treatment for MGD. In the present study, 73 patients were treated for 21 days with twice daily Blephasteam(®) sessions. The primary efficacy variable, a symptomatology visual analog scale score, declined from 63.07±21.23 (mean ± standard deviation) on day 0 to 41.90±25.49 on day 21. There were also improvements in a number of secondary efficacy variables including subjective ocular symptoms and clinical signs and symptoms of MGD and dry eye, though tear film breakup time and tear osmolarity were not improved. Global efficacy was assessed as satisfactory or very satisfactory in 83.8% of cases. Patient-reported subjective ocular symptoms declined during the study, and a majority of patients rated the efficacy of Blephasteam(®) as satisfactory or very satisfactory. Most patients found the device comfortable and were able to continue with normal activities (reading, watching TV, using a computer) during the Blephasteam(®) session. No safety or tolerability issues were identified. Dove Medical Press 2014-10-06 /pmc/articles/PMC4199825/ /pubmed/25336900 http://dx.doi.org/10.2147/OPTH.S68201 Text en © 2014 Benitez del Castillo et al. This work is published by Dove Medical Press Limited, and licensed under Creative Commons Attribution – Non Commercial (unported, v3.0) License The full terms of the License are available at http://creativecommons.org/licenses/by-nc/3.0/. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed.
spellingShingle Original Research
Benitez del Castillo, José Manuel
Kaercher, Thomas
Mansour, Khaled
Wylegala, Edward
Dua, Harminder
Evaluation of the efficacy, safety, and acceptability of an eyelid warming device for the treatment of meibomian gland dysfunction
title Evaluation of the efficacy, safety, and acceptability of an eyelid warming device for the treatment of meibomian gland dysfunction
title_full Evaluation of the efficacy, safety, and acceptability of an eyelid warming device for the treatment of meibomian gland dysfunction
title_fullStr Evaluation of the efficacy, safety, and acceptability of an eyelid warming device for the treatment of meibomian gland dysfunction
title_full_unstemmed Evaluation of the efficacy, safety, and acceptability of an eyelid warming device for the treatment of meibomian gland dysfunction
title_short Evaluation of the efficacy, safety, and acceptability of an eyelid warming device for the treatment of meibomian gland dysfunction
title_sort evaluation of the efficacy, safety, and acceptability of an eyelid warming device for the treatment of meibomian gland dysfunction
topic Original Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4199825/
https://www.ncbi.nlm.nih.gov/pubmed/25336900
http://dx.doi.org/10.2147/OPTH.S68201
work_keys_str_mv AT benitezdelcastillojosemanuel evaluationoftheefficacysafetyandacceptabilityofaneyelidwarmingdeviceforthetreatmentofmeibomianglanddysfunction
AT kaercherthomas evaluationoftheefficacysafetyandacceptabilityofaneyelidwarmingdeviceforthetreatmentofmeibomianglanddysfunction
AT mansourkhaled evaluationoftheefficacysafetyandacceptabilityofaneyelidwarmingdeviceforthetreatmentofmeibomianglanddysfunction
AT wylegalaedward evaluationoftheefficacysafetyandacceptabilityofaneyelidwarmingdeviceforthetreatmentofmeibomianglanddysfunction
AT duaharminder evaluationoftheefficacysafetyandacceptabilityofaneyelidwarmingdeviceforthetreatmentofmeibomianglanddysfunction