Structural mechanism of glutamate receptor activation and desensitization

Ionotropic glutamate receptors are ligand-gated ion channels that mediate excitatory synaptic transmission in the vertebrate brain. To better understand how structural changes gate ion flux across the membrane, we trapped AMPA and kainate receptor subtypes in their major functional states and analyz...

Descripción completa

Detalles Bibliográficos
Autores principales: Meyerson, Joel R., Kumar, Janesh, Chittori, Sagar, Rao, Prashant, Pierson, Jason, Bartesaghi, Alberto, Mayer, Mark L., Subramaniam, Sriram
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4199900/
https://www.ncbi.nlm.nih.gov/pubmed/25119039
http://dx.doi.org/10.1038/nature13603

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4199900/
https://www.ncbi.nlm.nih.gov/pubmed/25119039
http://dx.doi.org/10.1038/nature13603

Ejemplares similares