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Structural mechanism of glutamate receptor activation and desensitization

Ionotropic glutamate receptors are ligand-gated ion channels that mediate excitatory synaptic transmission in the vertebrate brain. To better understand how structural changes gate ion flux across the membrane, we trapped AMPA and kainate receptor subtypes in their major functional states and analyz...

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Detalles Bibliográficos
Autores principales:	Meyerson, Joel R., Kumar, Janesh, Chittori, Sagar, Rao, Prashant, Pierson, Jason, Bartesaghi, Alberto, Mayer, Mark L., Subramaniam, Sriram
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2014
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4199900/ https://www.ncbi.nlm.nih.gov/pubmed/25119039 http://dx.doi.org/10.1038/nature13603

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