Cargando…

Head and neck cancer relapse after chemoradiotherapy correlates with CD163+ macrophages in primary tumour and CD11b+ myeloid cells in recurrences

BACKGROUND: We investigated the prognostic role of tumour-associated macrophages (TAMs) in patients with head and neck squamous cell carcinoma (HNSCC) treated with definitive chemoradiotherapy (CRT). METHODS: The expression of CD68+, CD163+ and CD11b+ cells was assessed using immunohistochemistry in...

Descripción completa

Detalles Bibliográficos
Autores principales:	Balermpas, P, Rödel, F, Liberz, R, Oppermann, J, Wagenblast, J, Ghanaati, S, Harter, P N, Mittelbronn, M, Weiss, C, Rödel, C, Fokas, E
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2014
Materias:	Clinical Study
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4200089/ https://www.ncbi.nlm.nih.gov/pubmed/25093488 http://dx.doi.org/10.1038/bjc.2014.446

Ejemplares similares

Tumour-infiltrating lymphocytes predict response to definitive chemoradiotherapy in head and neck cancer
por: Balermpas, P, et al.
Publicado: (2014)

Tumour-infiltrating lymphocytes predict response to definitive chemoradiotherapy in head and neck cancer
por: Balermpas, P, et al.
Publicado: (2014)

Peripheral Leukocytosis Is Inversely Correlated with Intratumoral CD8+ T-Cell Infiltration and Associated with Worse Outcome after Chemoradiotherapy in Anal Cancer
por: Martin, Daniel, et al.
Publicado: (2017)

C-Reactive Protein-to-Albumin Ratio as Prognostic Marker for Anal Squamous Cell Carcinoma Treated With Chemoradiotherapy
por: Martin, Daniel, et al.
Publicado: (2019)

Chemoradiotherapy as Definitive Treatment for Elderly Patients with Head and Neck Cancer
por: Müller von der Grün, Jens, et al.
Publicado: (2018)

Merkel Cell Polyoma Viral Load and Intratumoral CD8+ Lymphocyte Infiltration Predict Overall Survival in Patients With Merkel Cell Carcinoma
por: von der Grün, Jens, et al.
Publicado: (2019)

Complete response after chemoradiotherapy for rectal cancer: what is the reasonable approach?
por: Rödel, Claus, et al.
Publicado: (2017)

Radiation Sensitization of Basal Cell and Head and Neck Squamous Cell Carcinoma by the Hedgehog Pathway Inhibitor Vismodegib
por: Hehlgans, Stephanie, et al.
Publicado: (2018)

Targeted Therapies and Immune-Checkpoint Inhibition in Head and Neck Squamous Cell Carcinoma: Where Do We Stand Today and Where to Go?
por: von der Grün, Jens, et al.
Publicado: (2019)

Polo-like kinase 3 and phosphoT273 caspase-8 are associated with improved local tumor control and survival in patients with anal carcinoma treated with concomitant chemoradiotherapy
por: Rödel, Franz, et al.
Publicado: (2016)

Sarcopenia Is Associated With Hematologic Toxicity During Chemoradiotherapy in Patients With Anal Carcinoma
por: Martin, Daniel, et al.
Publicado: (2020)

Neoadjuvant Chemoradiotherapy for Oral Cavity Cancer: Predictive Factors for Response and Interim Analysis of the Prospective INVERT-Trial
por: von der Grün, Jens, et al.
Publicado: (2022)

Diagnostic and treatment modalities for patients with cervical lymph node metastases of unknown primary site – current status and challenges
por: Müller von der Grün, Jens, et al.
Publicado: (2017)

Soluble ectodomain CD163 and extracellular vesicle-associated CD163 are two differently regulated forms of ‘soluble CD163’ in plasma
por: Etzerodt, Anders, et al.
Publicado: (2017)

Re-irradiation with concurrent and maintenance nivolumab in locally recurrent and inoperable squamous cell carcinoma of the head and neck: A single-center cohort study
por: Altay-Langguth, Alev, et al.
Publicado: (2021)

C-Reactive Protein to Albumin Ratio as Prognostic Marker in Locally Advanced Non-Small Cell Lung Cancer Treated with Chemoradiotherapy
por: Frey, Alina, et al.
Publicado: (2022)

Relationship Between sCD163 and mCD163 and Their Implication in the Detection and Typing of Leprosy
por: Farag, Azza Gaber Antar, et al.
Publicado: (2020)

ACO/ARO/AIO-21 - Capecitabine-based chemoradiotherapy in combination with the IL-1 receptor antagonist anakinra for rectal cancer Patients: A phase I trial of the German rectal cancer study group
por: Fleischmann, Maximilian, et al.
Publicado: (2022)

Definitive, Preoperative, and Palliative Radiation Therapy of Esophageal Cancer
por: Fokas, Emmanouil, et al.
Publicado: (2015)

Präoperative Therapie des Rektumkarzinoms – Kritische Anmerkungen zur amerikanischen PROSPECT-Studie
por: Fokas, Emmanouil, et al.
Publicado: (2023)

Differential association of CD68(+) and CD163(+) macrophages with macrophage enzymes, whole tumour gene expression and overall survival in advanced melanoma
por: Tremble, Liam Friel, et al.
Publicado: (2020)

Tumor Suppressor Protein p53 and Inhibitor of Apoptosis Proteins in Colorectal Cancer—A Promising Signaling Network for Therapeutic Interventions
por: Güllülü, Ömer, et al.
Publicado: (2021)

Patterns of care, toxicity and outcome in the treatment of salivary gland carcinomas: long-term experience from a tertiary cancer center
por: von der Grün, Jens, et al.
Publicado: (2021)

Clinical Significance of Soluble Hemoglobin Scavenger Receptor CD163 (sCD163) in Sepsis, a Prospective Study
por: Feng, Lin, et al.
Publicado: (2012)

Soluble CD163 and CD163 Expression on Monocytes Associated with Chronic Hepatitis B Inflammation and HBsAg Loss
por: Xie, Peilin, et al.
Publicado: (2022)

Soluble CD 163: A novel biomarker
por: Ahuja, Rajeev B.
Publicado: (2011)

CD14+CD16+ and CD14+CD163+ monocyte subpopulations in kidney allograft transplantation
por: Sekerkova, Alena, et al.
Publicado: (2014)

Kurzzeitstrahlentherapie mit 5 × 5 Gy gefolgt von präoperativer Chemotherapie und Resektion bei Patienten mit lokal fortgeschrittenen Rektumkarzinomen führt zu einer Verbesserung des krankheitsfreien Überlebens
por: Kirste, Simon, et al.
Publicado: (2021)

Kein Vorteil für die lokale Kontrolle nach Dosiseskalation der Strahlentherapie bei Patienten mit Ösophaguskarzinom nach einer definitiven Radiochemotherapie: randomisierte Phase-III-Studie ARTDECO
por: Fokas, Emmanouil, et al.
Publicado: (2022)

Eine Monotherapie mit Immuncheckpointblockade führt bei Patienten mit Rektumkarzinom und Mikrosatelliteninstabilität zur klinischen Komplettremission
por: Diefenhardt, Markus, et al.
Publicado: (2022)

High survivin expression as a risk factor in patients with anal carcinoma treated with concurrent chemoradiotherapy
por: Fraunholz, Ingeborg, et al.
Publicado: (2012)

The Clinical Significance of the CD163+ and CD68+ Macrophages in Patients with Hepatocellular Carcinoma
por: Kong, Ling-Qun, et al.
Publicado: (2013)

In vitro Phenotype Induction of Circulating Monocytes: CD16 and CD163 Analysis
por: Karsulovic, Claudio, et al.
Publicado: (2021)

Urinary soluble CD163 as a biomarker of disease activity and relapse in antineutrophil cytoplasm antibody-associated glomerulonephritis
por: Villacorta, Javier, et al.
Publicado: (2020)

CD163+ immune cell infiltrates and presence of CD54+ microvessels are prognostic markers for patients with embryonal rhabdomyosarcoma
por: Kather, Jakob Nikolas, et al.
Publicado: (2019)

Local production of soluble CD163 in the spondyloarthropathic joint
por: Baeten, D, et al.
Publicado: (2003)

Targeting of CD163(+) Macrophages in Inflammatory and Malignant Diseases
por: Skytthe, Maria K., et al.
Publicado: (2020)

Relevance of TMPRSS2, CD163/CD206, and CD33 in clinical severity stratification of COVID-19
por: Martínez-Diz, Silvia, et al.
Publicado: (2023)

Prognostic and predictive value of CD163 expression and the CD163/CD68 expression ratio for response to adjuvant chemotherapy in patients with surgically resected lung squamous cell carcinoma
por: Yanagawa, Naoki, et al.
Publicado: (2023)

The SMAC mimetic BV6 sensitizes colorectal cancer cells to ionizing radiation by interfering with DNA repair processes and enhancing apoptosis
por: Hehlgans, Stephanie, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_8cdh76gkbcme0prhdc9st6hs43