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Genotranscriptomic meta-analysis of the Polycomb gene CBX2 in human cancers: initial evidence of an oncogenic role

BACKGROUND: Polycomb group (PcG) proteins are histone modifiers known to transcriptionally silence key tumour suppressor genes in multiple human cancers. The chromobox proteins (CBX2, 4, 6, 7, and 8) are critical components of PcG-mediated repression. Four of them have been associated with tumour bi...

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Detalles Bibliográficos
Autores principales:	Clermont, P-L, Sun, L, Crea, F, Thu, K L, Zhang, A, Parolia, A, Lam, W L, Helgason, C D
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2014
Materias:	Genetics and Genomics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4200100/ https://www.ncbi.nlm.nih.gov/pubmed/25225902 http://dx.doi.org/10.1038/bjc.2014.474

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