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Simultaneous regeneration of full-thickness cartilage and subchondral bone defects in vivo using a three-dimensional scaffold-free autologous construct derived from high-density bone marrow-derived mesenchymal stem cells

BACKGROUND: In recent years, several methods have been developed for repairing full-thickness cartilage defects by tissue engineering using mesenchymal stem cells. Most of these use scaffolds to achieve sufficient thickness. However, considering the potential influence of scaffolds on the surroundin...

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Detalles Bibliográficos
Autores principales:	Ishihara, Kohei, Nakayama, Koichi, Akieda, Shizuka, Matsuda, Shuichi, Iwamoto, Yukihide
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4200118/ https://www.ncbi.nlm.nih.gov/pubmed/25312099 http://dx.doi.org/10.1186/s13018-014-0098-z

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