MicroRNA-188 suppresses G(1)/S transition by targeting multiple cyclin/CDK complexes

BACKGROUND: Accelerated cell cycle progression is the common feature of most cancers. MiRNAs can act as oncogenes or tumor suppressors by directly modulating cell cycle machinery. It has been shown that miR-188 is upregulated in UVB-irradiated mouse skin and human nasopharyngeal carcinoma CNE cells...

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Detalles Bibliográficos
Autores principales: Wu, Jiangbin, Lv, Qing, He, Jie, Zhang, Haoxiang, Mei, Xueshuang, Cui, Kai, Huang, Nunu, Xie, Weidong, Xu, Naihan, Zhang, Yaou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4200121/
https://www.ncbi.nlm.nih.gov/pubmed/25304455
http://dx.doi.org/10.1186/s12964-014-0066-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4200121/
https://www.ncbi.nlm.nih.gov/pubmed/25304455
http://dx.doi.org/10.1186/s12964-014-0066-6

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