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Infliximab reduces Zaprinast-induced retinal degeneration in cultures of porcine retina
BACKGROUND: cGMP-degrading phosphodiesterase 6 (PDE6) mutations cause around 4 to 5% of retinitis pigmentosa (RP), a rare form of retinal dystrophy. Growing evidence suggests that inflammation is involved in the progression of RP. The aims of this study were to corroborate the presence of high TNFα...
Autores principales: | Martínez-Fernández de la Cámara, Cristina, Olivares-González, Lorena, Hervás, David, Salom, David, Millán, José M, Rodrigo, Regina |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4200228/ https://www.ncbi.nlm.nih.gov/pubmed/25301432 http://dx.doi.org/10.1186/s12974-014-0172-9 |
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