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Challenges and Solutions to Pre- and Post-Randomization Subgroup Analyses

Subgroup analyses are commonly performed in the clinical trial setting with the purpose of illustrating that the treatment effect was consistent across different patient characteristics or identifying characteristics that should be targeted for treatment. There are statistical issues involved in per...

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Detalles Bibliográficos
Autores principales: Desai, Manisha, Pieper, Karen S., Mahaffey, Ken
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4200313/
https://www.ncbi.nlm.nih.gov/pubmed/25135344
http://dx.doi.org/10.1007/s11886-014-0531-2