Improvement of the Rett Syndrome Phenotype in a Mecp2 Mouse Model Upon Treatment with Levodopa and a Dopa-Decarboxylase Inhibitor

Rett Syndrome is a neurodevelopmental autism spectrum disorder caused by mutations in the gene coding for methyl CpG-binding protein (MeCP2). The disease is characterized by abnormal motor, respiratory, cognitive impairment, and autistic-like behaviors. No effective treatment of the disorder is avai...

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Detalles Bibliográficos
Autores principales: Szczesna, Karolina, de la Caridad, Olga, Petazzi, Paolo, Soler, Marta, Roa, Laura, Saez, Mauricio A, Fourcade, Stéphane, Pujol, Aurora, Artuch-Iriberri, Rafael, Molero-Luis, Marta, Vidal, August, Huertas, Dori, Esteller, Manel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4200495/
https://www.ncbi.nlm.nih.gov/pubmed/24917201
http://dx.doi.org/10.1038/npp.2014.136

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