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Comparison of the effect of intravenous ketamine and intramuscular ketamine for orthopedic procedures in children's sedation
BACKGROUND: Ketamine is used as a general anesthetic for short-term surgical procedures. The aim of this study is to compare the effect of intravenous (IV) ketamine and intramuscular (IM) ketamine in children admitted to the emergency department (ED). MATERIALS AND METHODS: This is a clinical trial...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Medknow Publications & Media Pvt Ltd
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4200543/ https://www.ncbi.nlm.nih.gov/pubmed/25337479 http://dx.doi.org/10.4103/2229-5151.141352 |
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author | Momeni, Mehdi Esfandbod, Mohsen Saeedi, Morteza Farnia, Mohamadreza Basirani, Roya Zebardast, Jeyran |
author_facet | Momeni, Mehdi Esfandbod, Mohsen Saeedi, Morteza Farnia, Mohamadreza Basirani, Roya Zebardast, Jeyran |
author_sort | Momeni, Mehdi |
collection | PubMed |
description | BACKGROUND: Ketamine is used as a general anesthetic for short-term surgical procedures. The aim of this study is to compare the effect of intravenous (IV) ketamine and intramuscular (IM) ketamine in children admitted to the emergency department (ED). MATERIALS AND METHODS: This is a clinical trial on 60 patients who were randomly classified into two groups. The first group received IV ketamine (1 mg/kg) and the second received IM ketamine (4 mg/kg). Data were collected before, during, and after the procedure. Time to reach sedation, severity of the sedation, and complications of the drug until discharge were studied. RESULTS: In this study, 60 patients were evaluated. The average length of the procedures was similar in both groups (P > 0.05). According to this study, sedation levels in the two groups in 5, 10, and 15 minutes did not show significant differences (P > 0.05), but there was a significant difference in sedation levels of patients in 30, 35, 40, and 45 minutes during sedation (P = 0.03, P = 0.04, P = 0.03 and P = 0.05). There was no significant difference in the incidence of complications between the two groups. DICUSSION: There was no significant difference in complications and level of sedation in both groups, but sedation was longer in the IM group; so, IV ketamine is the desirable approach for orthopedic procedures in sedating children. |
format | Online Article Text |
id | pubmed-4200543 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2014 |
publisher | Medknow Publications & Media Pvt Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-42005432014-10-21 Comparison of the effect of intravenous ketamine and intramuscular ketamine for orthopedic procedures in children's sedation Momeni, Mehdi Esfandbod, Mohsen Saeedi, Morteza Farnia, Mohamadreza Basirani, Roya Zebardast, Jeyran Int J Crit Illn Inj Sci Original Article BACKGROUND: Ketamine is used as a general anesthetic for short-term surgical procedures. The aim of this study is to compare the effect of intravenous (IV) ketamine and intramuscular (IM) ketamine in children admitted to the emergency department (ED). MATERIALS AND METHODS: This is a clinical trial on 60 patients who were randomly classified into two groups. The first group received IV ketamine (1 mg/kg) and the second received IM ketamine (4 mg/kg). Data were collected before, during, and after the procedure. Time to reach sedation, severity of the sedation, and complications of the drug until discharge were studied. RESULTS: In this study, 60 patients were evaluated. The average length of the procedures was similar in both groups (P > 0.05). According to this study, sedation levels in the two groups in 5, 10, and 15 minutes did not show significant differences (P > 0.05), but there was a significant difference in sedation levels of patients in 30, 35, 40, and 45 minutes during sedation (P = 0.03, P = 0.04, P = 0.03 and P = 0.05). There was no significant difference in the incidence of complications between the two groups. DICUSSION: There was no significant difference in complications and level of sedation in both groups, but sedation was longer in the IM group; so, IV ketamine is the desirable approach for orthopedic procedures in sedating children. Medknow Publications & Media Pvt Ltd 2014 /pmc/articles/PMC4200543/ /pubmed/25337479 http://dx.doi.org/10.4103/2229-5151.141352 Text en Copyright: © International Journal of Critical Illness and Injury Science http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Original Article Momeni, Mehdi Esfandbod, Mohsen Saeedi, Morteza Farnia, Mohamadreza Basirani, Roya Zebardast, Jeyran Comparison of the effect of intravenous ketamine and intramuscular ketamine for orthopedic procedures in children's sedation |
title | Comparison of the effect of intravenous ketamine and intramuscular ketamine for orthopedic procedures in children's sedation |
title_full | Comparison of the effect of intravenous ketamine and intramuscular ketamine for orthopedic procedures in children's sedation |
title_fullStr | Comparison of the effect of intravenous ketamine and intramuscular ketamine for orthopedic procedures in children's sedation |
title_full_unstemmed | Comparison of the effect of intravenous ketamine and intramuscular ketamine for orthopedic procedures in children's sedation |
title_short | Comparison of the effect of intravenous ketamine and intramuscular ketamine for orthopedic procedures in children's sedation |
title_sort | comparison of the effect of intravenous ketamine and intramuscular ketamine for orthopedic procedures in children's sedation |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4200543/ https://www.ncbi.nlm.nih.gov/pubmed/25337479 http://dx.doi.org/10.4103/2229-5151.141352 |
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