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Academic College of Emergency Experts in India's INDO-US Joint Working Group and OPUS12 Foundation Consensus Statement on Creating A Coordinated, Multi-Disciplinary, Patient-Centered, Global Point-of-Care Biomarker Discovery Network

Biomarker science brings great promise to clinical medicine. This is especially true in the era of technology miniaturization, rapid dissemination of knowledge, and point-of-care (POC) implementation of novel diagnostics. Despite this tremendous progress, the journey from a candidate biomarker to a...

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Autores principales: Stawicki, Stanislaw P., Stoltzfus, Jill C., Aggarwal, Praveen, Bhoi, Sanjeev, Bhatt, Shashi, Kalra, O. P., Bhalla, Ashish, Hoey, Brian A., Galwankar, Sagar C., Paladino, Lorenzo, Papadimos, Thomas J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4200545/
https://www.ncbi.nlm.nih.gov/pubmed/25337481
http://dx.doi.org/10.4103/2229-5151.141398
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author Stawicki, Stanislaw P.
Stoltzfus, Jill C.
Aggarwal, Praveen
Bhoi, Sanjeev
Bhatt, Shashi
Kalra, O. P.
Bhalla, Ashish
Hoey, Brian A.
Galwankar, Sagar C.
Paladino, Lorenzo
Papadimos, Thomas J.
author_facet Stawicki, Stanislaw P.
Stoltzfus, Jill C.
Aggarwal, Praveen
Bhoi, Sanjeev
Bhatt, Shashi
Kalra, O. P.
Bhalla, Ashish
Hoey, Brian A.
Galwankar, Sagar C.
Paladino, Lorenzo
Papadimos, Thomas J.
author_sort Stawicki, Stanislaw P.
collection PubMed
description Biomarker science brings great promise to clinical medicine. This is especially true in the era of technology miniaturization, rapid dissemination of knowledge, and point-of-care (POC) implementation of novel diagnostics. Despite this tremendous progress, the journey from a candidate biomarker to a scientifically validated biomarker continues to be an arduous one. In addition to substantial financial resources, biomarker research requires considerable expertise and a multidisciplinary approach. Investigational designs must also be taken into account, with the randomized controlled trial remaining the “gold standard”. The authors present a condensed overview of biomarker science and associated investigational methods, followed by specific examples from clinical areas where biomarker development and/or implementation resulted in tangible enhancements in patient care. This manuscript also serves as a call to arms for the establishment of a truly global, well-coordinated infrastructure dedicated to biomarker research and development, with focus on delivery of the latest discoveries directly to the patient via point-of-care technology.
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spelling pubmed-42005452014-10-21 Academic College of Emergency Experts in India's INDO-US Joint Working Group and OPUS12 Foundation Consensus Statement on Creating A Coordinated, Multi-Disciplinary, Patient-Centered, Global Point-of-Care Biomarker Discovery Network Stawicki, Stanislaw P. Stoltzfus, Jill C. Aggarwal, Praveen Bhoi, Sanjeev Bhatt, Shashi Kalra, O. P. Bhalla, Ashish Hoey, Brian A. Galwankar, Sagar C. Paladino, Lorenzo Papadimos, Thomas J. Int J Crit Illn Inj Sci Position Paper Biomarker science brings great promise to clinical medicine. This is especially true in the era of technology miniaturization, rapid dissemination of knowledge, and point-of-care (POC) implementation of novel diagnostics. Despite this tremendous progress, the journey from a candidate biomarker to a scientifically validated biomarker continues to be an arduous one. In addition to substantial financial resources, biomarker research requires considerable expertise and a multidisciplinary approach. Investigational designs must also be taken into account, with the randomized controlled trial remaining the “gold standard”. The authors present a condensed overview of biomarker science and associated investigational methods, followed by specific examples from clinical areas where biomarker development and/or implementation resulted in tangible enhancements in patient care. This manuscript also serves as a call to arms for the establishment of a truly global, well-coordinated infrastructure dedicated to biomarker research and development, with focus on delivery of the latest discoveries directly to the patient via point-of-care technology. Medknow Publications & Media Pvt Ltd 2014 /pmc/articles/PMC4200545/ /pubmed/25337481 http://dx.doi.org/10.4103/2229-5151.141398 Text en Copyright: © International Journal of Critical Illness and Injury Science http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Position Paper
Stawicki, Stanislaw P.
Stoltzfus, Jill C.
Aggarwal, Praveen
Bhoi, Sanjeev
Bhatt, Shashi
Kalra, O. P.
Bhalla, Ashish
Hoey, Brian A.
Galwankar, Sagar C.
Paladino, Lorenzo
Papadimos, Thomas J.
Academic College of Emergency Experts in India's INDO-US Joint Working Group and OPUS12 Foundation Consensus Statement on Creating A Coordinated, Multi-Disciplinary, Patient-Centered, Global Point-of-Care Biomarker Discovery Network
title Academic College of Emergency Experts in India's INDO-US Joint Working Group and OPUS12 Foundation Consensus Statement on Creating A Coordinated, Multi-Disciplinary, Patient-Centered, Global Point-of-Care Biomarker Discovery Network
title_full Academic College of Emergency Experts in India's INDO-US Joint Working Group and OPUS12 Foundation Consensus Statement on Creating A Coordinated, Multi-Disciplinary, Patient-Centered, Global Point-of-Care Biomarker Discovery Network
title_fullStr Academic College of Emergency Experts in India's INDO-US Joint Working Group and OPUS12 Foundation Consensus Statement on Creating A Coordinated, Multi-Disciplinary, Patient-Centered, Global Point-of-Care Biomarker Discovery Network
title_full_unstemmed Academic College of Emergency Experts in India's INDO-US Joint Working Group and OPUS12 Foundation Consensus Statement on Creating A Coordinated, Multi-Disciplinary, Patient-Centered, Global Point-of-Care Biomarker Discovery Network
title_short Academic College of Emergency Experts in India's INDO-US Joint Working Group and OPUS12 Foundation Consensus Statement on Creating A Coordinated, Multi-Disciplinary, Patient-Centered, Global Point-of-Care Biomarker Discovery Network
title_sort academic college of emergency experts in india's indo-us joint working group and opus12 foundation consensus statement on creating a coordinated, multi-disciplinary, patient-centered, global point-of-care biomarker discovery network
topic Position Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4200545/
https://www.ncbi.nlm.nih.gov/pubmed/25337481
http://dx.doi.org/10.4103/2229-5151.141398
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