Cargando…
Ultrasound guided neural stem cell transplantation through the lateral ventricle for treatment of cerebral palsy in children☆
A total of 24 children with cerebral palsy were enrolled in this study and underwent ultrasound guided transplantation of neural stem cells through the lateral ventricle. Neural stem cells (3.8 × 10(6)–7.3 × 10(7)) were injected into the lateral ventricles. Mild injury of lateral ventricular blood v...
Autores principales: | , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Medknow Publications & Media Pvt Ltd
2012
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4200709/ https://www.ncbi.nlm.nih.gov/pubmed/25337105 http://dx.doi.org/10.3969/j.issn.1673-5374.2012.32.007 |
_version_ | 1782340082785583104 |
---|---|
author | He, Sheng Luan, Zuo Qu, Suqing Qiu, Xuan Xin, Daqing Jia, Wenkai Shen, Yanhua Yu, Zehui Xu, Tao |
author_facet | He, Sheng Luan, Zuo Qu, Suqing Qiu, Xuan Xin, Daqing Jia, Wenkai Shen, Yanhua Yu, Zehui Xu, Tao |
author_sort | He, Sheng |
collection | PubMed |
description | A total of 24 children with cerebral palsy were enrolled in this study and underwent ultrasound guided transplantation of neural stem cells through the lateral ventricle. Neural stem cells (3.8 × 10(6)–7.3 × 10(7)) were injected into the lateral ventricles. Mild injury of lateral ventricular blood vessels occurred in only two cases (8.3%). Seven cases (29.2%) experienced a fever. Clinical manifestations were improved to varying degrees in eight cases (28.0%) within 3 months after transplantation. Patient condition did not worsen, and no patient experienced severe adverse reactions. |
format | Online Article Text |
id | pubmed-4200709 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2012 |
publisher | Medknow Publications & Media Pvt Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-42007092014-10-21 Ultrasound guided neural stem cell transplantation through the lateral ventricle for treatment of cerebral palsy in children☆ He, Sheng Luan, Zuo Qu, Suqing Qiu, Xuan Xin, Daqing Jia, Wenkai Shen, Yanhua Yu, Zehui Xu, Tao Neural Regen Res Article A total of 24 children with cerebral palsy were enrolled in this study and underwent ultrasound guided transplantation of neural stem cells through the lateral ventricle. Neural stem cells (3.8 × 10(6)–7.3 × 10(7)) were injected into the lateral ventricles. Mild injury of lateral ventricular blood vessels occurred in only two cases (8.3%). Seven cases (29.2%) experienced a fever. Clinical manifestations were improved to varying degrees in eight cases (28.0%) within 3 months after transplantation. Patient condition did not worsen, and no patient experienced severe adverse reactions. Medknow Publications & Media Pvt Ltd 2012-11-15 /pmc/articles/PMC4200709/ /pubmed/25337105 http://dx.doi.org/10.3969/j.issn.1673-5374.2012.32.007 Text en Copyright: © Neural Regeneration Research http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Article He, Sheng Luan, Zuo Qu, Suqing Qiu, Xuan Xin, Daqing Jia, Wenkai Shen, Yanhua Yu, Zehui Xu, Tao Ultrasound guided neural stem cell transplantation through the lateral ventricle for treatment of cerebral palsy in children☆ |
title | Ultrasound guided neural stem cell transplantation through the lateral ventricle for treatment of cerebral palsy in children☆ |
title_full | Ultrasound guided neural stem cell transplantation through the lateral ventricle for treatment of cerebral palsy in children☆ |
title_fullStr | Ultrasound guided neural stem cell transplantation through the lateral ventricle for treatment of cerebral palsy in children☆ |
title_full_unstemmed | Ultrasound guided neural stem cell transplantation through the lateral ventricle for treatment of cerebral palsy in children☆ |
title_short | Ultrasound guided neural stem cell transplantation through the lateral ventricle for treatment of cerebral palsy in children☆ |
title_sort | ultrasound guided neural stem cell transplantation through the lateral ventricle for treatment of cerebral palsy in children☆ |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4200709/ https://www.ncbi.nlm.nih.gov/pubmed/25337105 http://dx.doi.org/10.3969/j.issn.1673-5374.2012.32.007 |
work_keys_str_mv | AT hesheng ultrasoundguidedneuralstemcelltransplantationthroughthelateralventriclefortreatmentofcerebralpalsyinchildren AT luanzuo ultrasoundguidedneuralstemcelltransplantationthroughthelateralventriclefortreatmentofcerebralpalsyinchildren AT qusuqing ultrasoundguidedneuralstemcelltransplantationthroughthelateralventriclefortreatmentofcerebralpalsyinchildren AT qiuxuan ultrasoundguidedneuralstemcelltransplantationthroughthelateralventriclefortreatmentofcerebralpalsyinchildren AT xindaqing ultrasoundguidedneuralstemcelltransplantationthroughthelateralventriclefortreatmentofcerebralpalsyinchildren AT jiawenkai ultrasoundguidedneuralstemcelltransplantationthroughthelateralventriclefortreatmentofcerebralpalsyinchildren AT shenyanhua ultrasoundguidedneuralstemcelltransplantationthroughthelateralventriclefortreatmentofcerebralpalsyinchildren AT yuzehui ultrasoundguidedneuralstemcelltransplantationthroughthelateralventriclefortreatmentofcerebralpalsyinchildren AT xutao ultrasoundguidedneuralstemcelltransplantationthroughthelateralventriclefortreatmentofcerebralpalsyinchildren |