Heat-sensitive moxibustion attenuates the inflammation after focal cerebral ischemia/ reperfusion injury☆

Heat-sensitive moxibustion has neuroprotective effects against focal cerebral ischemia/reperfusion injury, however its mechanism of action remains unclear. In this study, rat models of focal cerebral ischemia/reperfusion injury were treated with suspended moxibustion at acupoint Dazhui (DU14) for 35...

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Autores principales: Xiao, Aijiao, Chen, Rixin, Kang, Mingfei, Tan, Shenghai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2012
Materias:
Acupuncture and Moxibustion and Neural Regeneration
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4200727/
https://www.ncbi.nlm.nih.gov/pubmed/25368636
http://dx.doi.org/10.3969/j.issn.1673-5374.2012.33.005
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author Xiao, Aijiao
Chen, Rixin
Kang, Mingfei
Tan, Shenghai
author_facet Xiao, Aijiao
Chen, Rixin
Kang, Mingfei
Tan, Shenghai
author_sort Xiao, Aijiao
collection PubMed
description Heat-sensitive moxibustion has neuroprotective effects against focal cerebral ischemia/reperfusion injury, however its mechanism of action remains unclear. In this study, rat models of focal cerebral ischemia/reperfusion injury were treated with suspended moxibustion at acupoint Dazhui (DU14) for 35 minutes. Results showed that suspended moxibustion decreased infarct volume, reduced cortical myeloperoxidase activity, and suppressed serum levels of proinflammatory cytokines in rats with focal cerebral ischemia/reperfusion injury. Our experimental findings indicated that heat-sensitive moxibustion can attenuate inflammation and promote repair after focal cerebral ischemia/reperfusion injury.
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spelling pubmed-42007272014-11-03 Heat-sensitive moxibustion attenuates the inflammation after focal cerebral ischemia/ reperfusion injury☆ Xiao, Aijiao Chen, Rixin Kang, Mingfei Tan, Shenghai Neural Regen Res Acupuncture and Moxibustion and Neural Regeneration Heat-sensitive moxibustion has neuroprotective effects against focal cerebral ischemia/reperfusion injury, however its mechanism of action remains unclear. In this study, rat models of focal cerebral ischemia/reperfusion injury were treated with suspended moxibustion at acupoint Dazhui (DU14) for 35 minutes. Results showed that suspended moxibustion decreased infarct volume, reduced cortical myeloperoxidase activity, and suppressed serum levels of proinflammatory cytokines in rats with focal cerebral ischemia/reperfusion injury. Our experimental findings indicated that heat-sensitive moxibustion can attenuate inflammation and promote repair after focal cerebral ischemia/reperfusion injury. Medknow Publications & Media Pvt Ltd 2012-11-25 /pmc/articles/PMC4200727/ /pubmed/25368636 http://dx.doi.org/10.3969/j.issn.1673-5374.2012.33.005 Text en Copyright: © Neural Regeneration Research http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Acupuncture and Moxibustion and Neural Regeneration
Xiao, Aijiao
Chen, Rixin
Kang, Mingfei
Tan, Shenghai
Heat-sensitive moxibustion attenuates the inflammation after focal cerebral ischemia/ reperfusion injury☆
title Heat-sensitive moxibustion attenuates the inflammation after focal cerebral ischemia/ reperfusion injury☆
title_full Heat-sensitive moxibustion attenuates the inflammation after focal cerebral ischemia/ reperfusion injury☆
title_fullStr Heat-sensitive moxibustion attenuates the inflammation after focal cerebral ischemia/ reperfusion injury☆
title_full_unstemmed Heat-sensitive moxibustion attenuates the inflammation after focal cerebral ischemia/ reperfusion injury☆
title_short Heat-sensitive moxibustion attenuates the inflammation after focal cerebral ischemia/ reperfusion injury☆
title_sort heat-sensitive moxibustion attenuates the inflammation after focal cerebral ischemia/ reperfusion injury☆
topic Acupuncture and Moxibustion and Neural Regeneration
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4200727/
https://www.ncbi.nlm.nih.gov/pubmed/25368636
http://dx.doi.org/10.3969/j.issn.1673-5374.2012.33.005
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