p62/Sequestosome 1 Regulates Aggresome Formation of Pathogenic Ataxin-3 with Expanded Polyglutamine

The cellular protein quality control system in association with aggresome formation contributes to protecting cells against aggregation-prone protein-induced toxicity. p62/Sequestosome 1 (p62) is a multifunctional protein which plays an important role in protein degradation and aggregation. Although...

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Detalles Bibliográficos
Autores principales: Zhou, Liang, Wang, Hongfeng, Chen, Dong, Gao, Feng, Ying, Zheng, Wang, Guanghui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4200763/
https://www.ncbi.nlm.nih.gov/pubmed/25158237
http://dx.doi.org/10.3390/ijms150914997

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4200763/
https://www.ncbi.nlm.nih.gov/pubmed/25158237
http://dx.doi.org/10.3390/ijms150914997

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