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p62/Sequestosome 1 Regulates Aggresome Formation of Pathogenic Ataxin-3 with Expanded Polyglutamine
The cellular protein quality control system in association with aggresome formation contributes to protecting cells against aggregation-prone protein-induced toxicity. p62/Sequestosome 1 (p62) is a multifunctional protein which plays an important role in protein degradation and aggregation. Although...
Autores principales: | Zhou, Liang, Wang, Hongfeng, Chen, Dong, Gao, Feng, Ying, Zheng, Wang, Guanghui |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4200763/ https://www.ncbi.nlm.nih.gov/pubmed/25158237 http://dx.doi.org/10.3390/ijms150914997 |
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