Cargando…

Melatonin Regulates Aging and Neurodegeneration through Energy Metabolism, Epigenetics, Autophagy and Circadian Rhythm Pathways

Brain aging is linked to certain types of neurodegenerative diseases and identifying new therapeutic targets has become critical. Melatonin, a pineal hormone, associates with molecules and signaling pathways that sense and influence energy metabolism, autophagy, and circadian rhythms, including insu...

Descripción completa

Detalles Bibliográficos
Autores principales:	Jenwitheesuk, Anorut, Nopparat, Chutikorn, Mukda, Sujira, Wongchitrat, Prapimpun, Govitrapong, Piyarat
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2014
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4200827/ https://www.ncbi.nlm.nih.gov/pubmed/25247581 http://dx.doi.org/10.3390/ijms150916848

Ejemplares similares

Melatonin regulates the aging mouse hippocampal homeostasis via the sirtuin1-FOXO1 pathway
por: Jenwitheesuk, Anorut, et al.
Publicado: (2017)

Long-term administration of melatonin attenuates neuroinflammation in the aged mouse brain
por: Permpoonputtana, Kannika, et al.
Publicado: (2018)

The role of melatonin in amyloid beta-induced inflammation mediated by inflammasome signaling in neuronal cell lines
por: Nopparat, Chutikorn, et al.
Publicado: (2023)

Role of Melatonin on Virus-Induced Neuropathogenesis—A Concomitant Therapeutic Strategy to Understand SARS-CoV-2 Infection
por: Wongchitrat, Prapimpun, et al.
Publicado: (2021)

Role of Melatonin in Reducing Amphetamine-Induced Degeneration in Substantia Nigra of Rats via Calpain and Calpastatin Interaction
por: Chetsawang, Jirapa, et al.
Publicado: (2017)

Antiviral effect of melatonin on Japanese encephalitis virus infection involves inhibition of neuronal apoptosis and neuroinflammation in SH-SY5Y cells
por: Kitidee, Kuntida, et al.
Publicado: (2023)

Elevation of Cleaved p18 Bax Levels Associated with the Kinetics of Neuronal Cell Death during Japanese Encephalitis Virus Infection
por: Wongchitrat, Prapimpun, et al.
Publicado: (2019)

Mood Disorders, Circadian Rhythms, Melatonin and Melatonin Agonists
por: Quera Salva, M.A., et al.
Publicado: (2012)

Comparison of melatonin with growth factors in promoting precursor cells proliferation in adult mouse subventricular zone
por: Sotthibundhu, Areechun, et al.
Publicado: (2016)

Mechanisms of Melatonin in Alleviating Alzheimer’s Disease
por: Shukla, Mayuri, et al.
Publicado: (2017)

Circadian Rhythm Dysregulation and Restoration: The Role of Melatonin
por: Vasey, Clayton, et al.
Publicado: (2021)

Melatonin, circadian rhythms and glaucoma: current perspective
por: Gubin, Denis, et al.
Publicado: (2022)

Butein, isoliquiritigenin, and scopoletin attenuate neurodegeneration via antioxidant enzymes and SIRT1/ADAM10 signaling pathway
por: Gay, Naw Hser, et al.
Publicado: (2020)

Falls Risk, Circadian Rhythms and Melatonin: Current Perspectives
por: Goswami, Nandu, et al.
Publicado: (2020)

Influence of Circadian Rhythm in the Eye: Significance of Melatonin in Glaucoma
por: Martínez-Águila, Alejandro, et al.
Publicado: (2021)

Circadian Rhythms and Melatonin Metabolism in Patients With Disorders of Gut-Brain Interactions
por: Fowler, Sophie, et al.
Publicado: (2022)

Rheostatic Balance of Circadian Rhythm and Autophagy in Metabolism and Disease
por: Wang, Xiang, et al.
Publicado: (2020)

Protecting the Melatonin Rhythm through Circadian Healthy Light Exposure
por: Bonmati-Carrion, Maria Angeles, et al.
Publicado: (2014)

Diabetes and atherothrombosis: The circadian rhythm and role of melatonin in vascular protection
por: Otamas, Anastasia, et al.
Publicado: (2020)

Virtual discovery of melatonin receptor ligands to modulate circadian rhythms
por: Stein, Reed M., et al.
Publicado: (2020)

Neurodegeneration, memory loss, and dementia: the impact of biological clocks and circadian rhythm
por: Maiese, Kenneth
Publicado: (2021)

New perspectives on the role of melatonin in human sleep, circadian rhythms and their regulation
por: Zisapel, Nava
Publicado: (2018)

Circadian Rhythm and CKD: Is Melatonin a Key Player or Bi-player?
por: Nagasawa, Yasuyuki, et al.
Publicado: (2019)

Ruminal Microbes Exhibit a Robust Circadian Rhythm and Are Sensitive to Melatonin
por: Ouyang, Jialiang, et al.
Publicado: (2021)

Effect of night-shift work on cortisol circadian rhythm and melatonin levels
por: Brum, Maria Carlota Borba, et al.
Publicado: (2022)

Expression and Distribution Pattern of Pnn in Ischemic Cerebral Cortex and Cultured Neural Cells Exposed to Oxygen-Glucose Deprivation
por: Hsu, Shu-Yuan, et al.
Publicado: (2020)

Editorial: Roles of Sleep Disruption and Circadian Rhythm Alterations on Neurodegeneration and Alzheimer's Disease
por: Duncan, Marilyn J., et al.
Publicado: (2021)

The circadian rhythm in intervertebral disc degeneration: an autophagy connection
por: Zhang, Tai-Wei, et al.
Publicado: (2020)

Pineal melatonin is a circadian time-giver for leptin rhythm in Syrian hamsters
por: Chakir, Ibtissam, et al.
Publicado: (2015)

Mechanism of Sleep Disturbance in Children with Atopic Dermatitis and the Role of the Circadian Rhythm and Melatonin
por: Chang, Yung-Sen, et al.
Publicado: (2016)

Diverse roles of mitochondria in ischemic stroke
por: Yang, Jenq-Lin, et al.
Publicado: (2018)

Epigenetic Clock and Circadian Rhythms in Stem Cell Aging and Rejuvenation
por: Samoilova, Ekaterina M., et al.
Publicado: (2021)

Differential Contribution of Rod and Cone Circadian Clocks in Driving Retinal Melatonin Rhythms in Xenopus
por: Hayasaka, Naoto, et al.
Publicado: (2010)

Comparative Review of Approved Melatonin Agonists for the Treatment of Circadian Rhythm Sleep‐Wake Disorders
por: Williams, Wilbur P. (Trey), et al.
Publicado: (2016)

Key Genes in the Melatonin Biosynthesis Pathway with Circadian Rhythm Are Associated with Various Abiotic Stresses
por: Ahn, Hye-Ryun, et al.
Publicado: (2021)

The Melatonin–Mitochondrial Axis: Engaging the Repercussions of Ultraviolet Radiation Photoaging on the Skin’s Circadian Rhythm
por: Gao, Ting, et al.
Publicado: (2023)

Healthier rhythm, healthier brain? Integrity of circadian melatonin and temperature rhythms relates to the clinical state of brain‐injured patients
por: Blume, C., et al.
Publicado: (2019)

Editorial: Circadian Rhythms and Metabolism
por: Challet, Etienne, et al.
Publicado: (2017)

Epigenetic Regulation of Circadian Rhythm and Its Possible Role in Diabetes Mellitus
por: Hudec, Michael, et al.
Publicado: (2020)

Eyeless Mexican Cavefish Save Energy by Eliminating the Circadian Rhythm in Metabolism
por: Moran, Damian, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_krj45cghdp705jrcma01dj0a91