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Curcumin Induced Human Gastric Cancer BGC-823 Cells Apoptosis by ROS-Mediated ASK1-MKK4-JNK Stress Signaling Pathway

The signaling mediated by stress-activated MAP kinases (MAPK), c-Jun N-terminal kinase (JNK) has well-established importance in cancer. In the present report, we investigated the effects of curcumin on the signaling pathway in human gastric cancer BGC-823 cells. Curcumin induced reactive oxygen spec...

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Detalles Bibliográficos
Autores principales:	Liang, Tao, Zhang, Xiaojian, Xue, Wenhua, Zhao, Songfeng, Zhang, Xiang, Pei, Jianying
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2014
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4200840/ https://www.ncbi.nlm.nih.gov/pubmed/25198898 http://dx.doi.org/10.3390/ijms150915754

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