Cargando…

Metabolism of Cryptic Peptides Derived from Neuropeptide FF Precursors: The Involvement of Insulin-Degrading Enzyme

The term “cryptome” refers to the subset of cryptic peptides with bioactivities that are often unpredictable and very different from the parent protein. These cryptic peptides are generated by proteolytic cleavage of proteases, whose identification in vivo can be very challenging. In this work, we s...

Descripción completa

Detalles Bibliográficos
Autores principales:	Grasso, Giuseppe, Mielczarek, Przemyslaw, Niedziolka, Magdalena, Silberring, Jerzy
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2014
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4200852/ https://www.ncbi.nlm.nih.gov/pubmed/25247577 http://dx.doi.org/10.3390/ijms150916787

Ejemplares similares

The insulin-degrading enzyme as a link between insulin and neuropeptides metabolism
por: Wacławczyk, Dorota, et al.
Publicado: (2021)

IDE Degrades Nociceptin/Orphanin FQ through an Insulin Regulated Mechanism
por: Zingale, Gabriele Antonio, et al.
Publicado: (2019)

Synthesis of the Novel Covalent Cysteine Proteases Inhibitor with Iodoacetic Functional Group
por: Hartman, Kinga, et al.
Publicado: (2020)

Role of neuropeptide FF in central cardiovascular and neuroendocrine regulation
por: Jhamandas, Jack H., et al.
Publicado: (2013)

The hypothalamic neuropeptide FF network is impaired in hypertensive patients
por: Goncharuk, Valeri D, et al.
Publicado: (2014)

Nonpeptide Small Molecule Agonist and Antagonist Original Leads for Neuropeptide FF1 and FF2 Receptors
por: Journigan, V. Blair, et al.
Publicado: (2014)

Functional modulation of human delta opioid receptor by neuropeptide FF
por: Änkö, Minna-Liisa, et al.
Publicado: (2005)

Neuropeptide FF indirectly affects testicular morphogenesis and functions in medaka
por: Tomihara, Soma, et al.
Publicado: (2022)

Diet-induced adaptive thermogenesis requires neuropeptide FF receptor-2 signalling
por: Zhang, Lei, et al.
Publicado: (2018)

Transcriptomic Changes in Mouse Bone Marrow-Derived Macrophages Exposed to Neuropeptide FF
por: Sun, Yulong, et al.
Publicado: (2021)

Synthesis and characterisation of PEG-peptide surfaces for proteolytic enzyme detection
por: Trzcinska, Roza, et al.
Publicado: (2013)

Opposite Effects of Neuropeptide FF on Central Antinociception Induced by Endomorphin-1 and Endomorphin-2 in Mice
por: Wang, Zi-long, et al.
Publicado: (2014)

Neuropeptide FF receptor 2 inhibits capsaicin-induced CGRP Upregulation in mouse trigeminal ganglion
por: Lin, Ya-Tin, et al.
Publicado: (2020)

Intracerebroventricular Neuropeptide FF Diminishes the Number of Apneas and Cardiovascular Effects Produced by Opioid Receptors’ Activation
por: Wojciechowski, Piotr, et al.
Publicado: (2020)

Elevated Serum Neuropeptide FF Levels Are Associated with Cognitive Decline in Patients with Spinal Cord Injury
por: Sun, Shifei, et al.
Publicado: (2021)

Commentary on Ivancic et al.: Enzyme kinetics from circular dichroism of insulin reveals mechanistic insights into the regulation of insulin-degrading enzyme
por: Grasso, Giuseppe
Publicado: (2018)

Correction to: The knockdown of Neuropeptide FF receptor 2 inhibits capsaicin-induced CGRP Upregulation in mouse trigeminal ganglion
por: Lin, Ya-Tin, et al.
Publicado: (2020)

Evolution of Neuropeptide Precursors in Polyneoptera (Insecta)
por: Bläser, Marcel, et al.
Publicado: (2020)

Neuroprotective Effect of Carnosine Is Mediated by Insulin-Degrading Enzyme
por: Distefano, Alessia, et al.
Publicado: (2022)

Transcriptomic identification of starfish neuropeptide precursors yields new insights into neuropeptide evolution
por: Semmens, Dean C., et al.
Publicado: (2016)

S. A. ff. Dakin
Publicado: (1962)

Redox Regulation of Insulin Degradation by Insulin-Degrading Enzyme
por: Cordes, Crystal M., et al.
Publicado: (2011)

NeuroPID: a classifier of neuropeptide precursors
por: Karsenty, Solange, et al.
Publicado: (2014)

The ATP Synthase Subunits FfATPh, FfATP5, and FfATPb Regulate the Development, Pathogenicity, and Fungicide Sensitivity of Fusarium fujikuroi
por: Yang, Xin, et al.
Publicado: (2023)

Peptides and Peptidomimetics as Inhibitors of Enzymes Involved in Fibrillar Collagen Degradation
por: Ledwoń, Patrycja, et al.
Publicado: (2021)

Hemorphins—From Discovery to Functions and Pharmacology
por: Mielczarek, Przemyslaw, et al.
Publicado: (2021)

Identification of the neuropeptide precursor genes potentially involved in the larval settlement in the Echiuran worm Urechis unicinctus
por: Hou, Xitan, et al.
Publicado: (2020)

Discovery of novel representatives of bilaterian neuropeptide families and reconstruction of neuropeptide precursor evolution in ophiuroid echinoderms
por: Zandawala, Meet, et al.
Publicado: (2017)

Neuropeptide precursors and neuropeptides in the sea cucumber Apostichopus japonicus: a genomic, transcriptomic and proteomic analysis
por: Chen, Muyan, et al.
Publicado: (2019)

Highlights of H→ff at the LHC
por: Chen, Xin
Publicado: (2019)

NeuroPred: a tool to predict cleavage sites in neuropeptide precursors and provide the masses of the resulting peptides
por: Southey, Bruce R., et al.
Publicado: (2006)

Targeting Insulin-Degrading Enzyme in Insulin Clearance
por: Leissring, Malcolm A., et al.
Publicado: (2021)

Modulation of Insulin Sensitivity by Insulin-Degrading Enzyme
por: González-Casimiro, Carlos M., et al.
Publicado: (2021)

Expression of Neuropeptide FF Defines a Population of Excitatory Interneurons in the Superficial Dorsal Horn of the Mouse Spinal Cord that Respond to Noxious and Pruritic Stimuli
por: Gutierrez-Mecinas, Maria, et al.
Publicado: (2019)

Regulatory feedback cycle of the insulin‐degrading enzyme and the amyloid precursor protein intracellular domain: Implications for Alzheimer’s disease
por: Lauer, Anna A., et al.
Publicado: (2020)

Processing, Characterization of Furcraea foetida (FF) Fiber and Investigation of Physical/Mechanical Properties of FF/Epoxy Composite
por: Madival, Abhishek Sadananda, et al.
Publicado: (2022)

RNA-seq reveals post-transcriptional regulation of Drosophila insulin-like peptide dilp8 and the neuropeptide-like precursor Nplp2 by the exoribonuclease Pacman/XRN1
por: Jones, Christopher I., et al.
Publicado: (2016)

Inhibition of Insulin Degrading Enzyme and Insulin Degradation by UV-Killed Lactobacillus acidophilus
por: Neyazi, Nadia, et al.
Publicado: (2018)

Insulin-Degrading Enzyme: Paradoxes and Possibilities
por: Leissring, Malcolm A.
Publicado: (2021)

Once-daily fluticasone furoate (FF)/vilanterol reduces risk of severe exacerbations in asthma versus FF alone
por: Bateman, Eric D, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_nhgtj5i93u6q45ktlpjrcfehii