Structure Elucidation and Cytotoxic Evaluation of New Polyacetylenes from a Marine Sponge Petrosia sp.

The sponge Petrosia sp. yielded five polyacetylenic compounds (1–5), including two new polyacetylenes, petrosianynes A (1) and B (2). The structures of these compounds were elucidated by detailed spectroscopic analysis and by comparison with the physical and spectral data of related known analogues....

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Autores principales: Juan, Yung-Shun, Lee, Chien-Chih, Tsao, Chia-Wei, Lu, Mei-Chin, El-Shazly, Mohamed, Shih, Huei-Chuan, Chen, Yu-Cheng, Wu, Yang-Chang, Su, Jui-Hsin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4200862/
https://www.ncbi.nlm.nih.gov/pubmed/25238415
http://dx.doi.org/10.3390/ijms150916511
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author Juan, Yung-Shun
Lee, Chien-Chih
Tsao, Chia-Wei
Lu, Mei-Chin
El-Shazly, Mohamed
Shih, Huei-Chuan
Chen, Yu-Cheng
Wu, Yang-Chang
Su, Jui-Hsin
author_facet Juan, Yung-Shun
Lee, Chien-Chih
Tsao, Chia-Wei
Lu, Mei-Chin
El-Shazly, Mohamed
Shih, Huei-Chuan
Chen, Yu-Cheng
Wu, Yang-Chang
Su, Jui-Hsin
author_sort Juan, Yung-Shun
collection PubMed
description The sponge Petrosia sp. yielded five polyacetylenic compounds (1–5), including two new polyacetylenes, petrosianynes A (1) and B (2). The structures of these compounds were elucidated by detailed spectroscopic analysis and by comparison with the physical and spectral data of related known analogues. Compounds 1–5 exhibited significant cytotoxic activity against a limited panel of cancer cell lines.
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spelling pubmed-42008622014-10-17 Structure Elucidation and Cytotoxic Evaluation of New Polyacetylenes from a Marine Sponge Petrosia sp. Juan, Yung-Shun Lee, Chien-Chih Tsao, Chia-Wei Lu, Mei-Chin El-Shazly, Mohamed Shih, Huei-Chuan Chen, Yu-Cheng Wu, Yang-Chang Su, Jui-Hsin Int J Mol Sci Article The sponge Petrosia sp. yielded five polyacetylenic compounds (1–5), including two new polyacetylenes, petrosianynes A (1) and B (2). The structures of these compounds were elucidated by detailed spectroscopic analysis and by comparison with the physical and spectral data of related known analogues. Compounds 1–5 exhibited significant cytotoxic activity against a limited panel of cancer cell lines. MDPI 2014-09-18 /pmc/articles/PMC4200862/ /pubmed/25238415 http://dx.doi.org/10.3390/ijms150916511 Text en © 2014 by the authors; licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).
spellingShingle Article
Juan, Yung-Shun
Lee, Chien-Chih
Tsao, Chia-Wei
Lu, Mei-Chin
El-Shazly, Mohamed
Shih, Huei-Chuan
Chen, Yu-Cheng
Wu, Yang-Chang
Su, Jui-Hsin
Structure Elucidation and Cytotoxic Evaluation of New Polyacetylenes from a Marine Sponge Petrosia sp.
title Structure Elucidation and Cytotoxic Evaluation of New Polyacetylenes from a Marine Sponge Petrosia sp.
title_full Structure Elucidation and Cytotoxic Evaluation of New Polyacetylenes from a Marine Sponge Petrosia sp.
title_fullStr Structure Elucidation and Cytotoxic Evaluation of New Polyacetylenes from a Marine Sponge Petrosia sp.
title_full_unstemmed Structure Elucidation and Cytotoxic Evaluation of New Polyacetylenes from a Marine Sponge Petrosia sp.
title_short Structure Elucidation and Cytotoxic Evaluation of New Polyacetylenes from a Marine Sponge Petrosia sp.
title_sort structure elucidation and cytotoxic evaluation of new polyacetylenes from a marine sponge petrosia sp.
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4200862/
https://www.ncbi.nlm.nih.gov/pubmed/25238415
http://dx.doi.org/10.3390/ijms150916511
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