DYRK1A-mediated phosphorylation of GluN2A at Ser(1048) regulates the surface expression and channel activity of GluN1/GluN2A receptors

N-methyl-D-aspartate glutamate receptors (NMDARs) play a pivotal role in neural development and synaptic plasticity, as well as in neurological disease. Since NMDARs exert their function at the cell surface, their density in the plasma membrane is finely tuned by a plethora of molecules that regulat...

Descripción completa

Detalles Bibliográficos
Autores principales: Grau, Cristina, Arató, Krisztina, Fernández-Fernández, José M., Valderrama, Aitana, Sindreu, Carlos, Fillat, Cristina, Ferrer, Isidre, de la Luna, Susana, Altafaj, Xavier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4201086/
https://www.ncbi.nlm.nih.gov/pubmed/25368549
http://dx.doi.org/10.3389/fncel.2014.00331

Ejemplares similares

Ejemplares similares