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Endocannabinoid 2-Arachidonoylglycerol Self-Administration by Sprague-Dawley Rats and Stimulation of in vivo Dopamine Transmission in the Nucleus Accumbens Shell
2-Arachidonoylglycerol (2-AG) is the most potent endogenous ligand of brain cannabinoid CB(1) receptors and is synthesized on demand from 2-arachidonate-containing phosphoinositides by the action of diacylglycerol lipase in response to increased intracellular calcium. Several studies indicate that t...
Autores principales: | De Luca, Maria Antonietta, Valentini, Valentina, Bimpisidis, Zisis, Cacciapaglia, Fabio, Caboni, Pierluigi, Di Chiara, Gaetano |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4201088/ https://www.ncbi.nlm.nih.gov/pubmed/25368584 http://dx.doi.org/10.3389/fpsyt.2014.00140 |
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